Complexation papers

t h e Template E f f e c t.

Pederson noted

' the complexing a b i l i t y of crown e t h e r s with transition raetal, and ammonium c a t i o n s.

alkaline

earth, are

complexes and the

f o r m e d by i o n - d i p o l e i n t e r a c t i o n s between the charged oxygen atoms of the crown r i n g. formation and stability of these

negatively the

factors

affecting

cation-crown complexes have been i d e n t i f i e d and i n c l u d e : (1) the relative sizes of the ion and the hole in the polyether ring; (2) (3) (4) (5) (6) (7) (8) Depending and of the nuraber of oxygen atoras in the polyether ring; the coplanarity of the oxygen atoras; the symmetrical placement of the oxygen atoms; the basicity of the oxygen atoms; the steric hindrance in the polyether ring; the tendency of the ion to associate with the solvent; the electrical charge on the ion. on t h e r e l a t i o n s h i p between the " h o l e s i z e " in the crown
t h e i o n i c diaraeter of the c a t i o n , complexes may occur with r a t i o s 1:1, 2:1, 3:1, values of or 3:2 (crown ether:ion). and raetal ion Tables 1 and 2 give

accepted

cavity
d i a m e t e r s from which a
d e s i r e d " b e s t f i t " approximation can be made. The accounts the are template effect i s an unusual f e a t u r e of crown e t h e r s which
f o r the remarkably high y i e l d s o b t a i n e d in the s y n t h e s i s of p o l y e t h e r s , e s p e c i a l l y the l a r g e r i n g s. without using high dilution The high y i e l d s

cyclic

achieved
c o n d i t i o n s and can be
TABLE 1 Diameters of the Cavities

Crown Echer

12-Crown-4 I4-Crown-4 15-Crown-5 18-Crown-6 21-Crown-7

Diameter,

1.2 1.2-1.5 1.7-2.2 2.6-3.2 3.4-4.3
TABLE 2 3,6 Alkaline and Alkaline Earth Atomic Radii
Alkaline Cation Li"^ Na"^ K"^ Rb"^ Cs Fr"*"
Diameter, A 1.20 1.90 2.66 2.96 3.34 3.52
Alkaline Earth Cation Be^"^ Mg^* Ca^* Sr^"^ Ba Ra^"^
Diameter, X 0.62 1.30 1.98 2.26 2.70 2.80
7 attributed to this s p e c i a l effect. Evidence by Greene and Cook

moiety

mu s t b e

coraplex Pressraan alkali
f o r m a t i o n to o c c u r. 19 reported that earth

Using bulk phase ion the

n i g e r i c i n - t y pe a n t i b i o t i c s ions

and a l k a l i n e

a c r o s s l i p i d b a r r i e r s and
suggested He a l s o dipole raetal
the d e s i g n a t i o n " i o n o p h o r e s " for such compounds (Table 3 ).
r e p o r t e d t h a t metal c a t i o n complex fonnation i s via induced i n t e r a c t i o n s with the oxygen atoras and t h a t t r a n s p o r t of the

ions 2).

a n t i b i o t i c s i s in an e l e c t r i c a l l y n e u t r a l Lardy 20 showed that the

(Figure

In a d d i t i o n , monocarboxy1ic

naturally

occurring,

acid-type

antibiotics

cause l o s s of

potassium from mitochondria. Lipid Blayer Membrane and lon T r a n s p o r t. The b a r r i e r to ion
moveraent a c r o s s e i t h e r a b i o l o g i c a l or a model l i p i d b i l a y e r membrane is the organic i n t e r i o r through which the cation-complex raust raove.

Therefore, of the

the composition of the b a r r i e r i s important for the design e t h e r c a r b o x y l i c a c i d s and for the design of the model raerabrane for testing. Studies 22 have identified

crown bilayer

TABLE 3 Naturally Occurring, Monocarboxylic Acid Containing, Macrocyclic Antibiotics '
Antibiotic Dianemycin Monensin Nigericin X-206 X-537
lon Best Selected Na Na' K

Figure 2.

Monensin Complex
8 this interior t o b e an approximately 12:1 raolar r a t i o of decane to This a c c o u n t s for the very n o n p o l a r , low d i e l e c t r i c ( C) ). F u r t h e r m o r e , the araount of
p h o s pho 1 i p i d. raedia ion (D (decane, extracted = 9.08

D = 1.99

i s g r e a t l y reduced in changing from a dichloromethane to a toluene (D = 2. ( C ) ^ ^ ) model

(20C)^^) but

interior,

a more a c c u r a t e '

i n d i c a t i o n of c a t i o n s t a b i l i t y and
selectivity is obtained. The with is
t r a n s p o r t of metal c a t i o n s through a l i p i d b i l a y e r merabrane
the a i d of a monocarboxylic a c i d - t y p e a n t i b i o t i c or crown e t h e r , to occur by c a t i o n c o m p l e x a t i o n a t the b a s i c pH through

envisioned

aqueous-organic the the
i n t e r f a c e , followed by f a c i l i t a t e d d i f f u s i o n
n o n p o l a r o r g a n i c i n t e r i o r , and f i n a l l y , r e l e a s e of the c a t i o n at acidic pH a q u e o u s - o r g a n i c that and proton results interface. 25 In a d d i t i o n , i t is

suggested transport

t r a n s p o r t occurs in c o n j u n c t i o n with c a t i o n in a net exchange of a metal c a t i o n to the
a c i d i c s i d e of the b i l a y e r merabrane and a proton to the b a s i c s i d e. Previous deraonstrated raerabranes raacrocyclic unfavorable extraction model lipid by Synthesis of Crown C a r b o x y l i c Acids. From the
i o n s e l e c t i v i t y and t r a n s p o r t a b i l i t y a c r o s s b i o l o g i c a l the naturally o c c u r r i n g , monocarboxylic a c i d - t y p e , and the raore recently shown

antibiotics,

d i s t r i b u t i o n coefficients
for the normally encountered across raarkedly
c o u n t e r a n i o n s ( c h l o r i d e s , s u l f a t e s , and n i t r a t e s ) bilayer in the raerabranes, ' i n t e r e s t has been

stimulated

development
of the s y n t h e t i c a l ly simpler crown
c a r b o x y l i c a c i d s to rairaic t h e s e n a t u r a l l y o c c u r r i n g compounds. would p e r m i t f a c i l e v a r i a t i o n of the to exaraine the raacrocyclic on ring ion
These models size and the

1ipophi1icity and rate

influence

selectivity

of t r a n s p o r t.
C o n t r i b u t i o n s from two g r o u p s ,
C r a r a ' s and B a r t s c h ' s , account for the l a r g e m a j o r i t y of the s y n t h e t i c work in t h i s area. co-workers group
Cram a n d carboxylic "built-in" cavity
i n t r o d u c e d an i o n i z a b l e The
crown e t h e r (Table 4 ).
i o n i z a b l e u n i t i s a b l e to c e n t e r above or below the crown it t o function as an i n t e r n a l counteranion for the and thereby adding increased stability.

allowing

coraplexed

cation

Incor pora t i on of a binaphthyl unit directs the side chains under or over the cavity. More many crown recently, ethers Bartsch and co-workers have s y n t h e s i z e d

By p r o t o n a t i o n of interface, raetal
nitrogen release bound to
the a c i d i c aqueous-organic

cation is

facilitated.
A d i r e c t e x c h a n g e o c c u r s , and t h e p r o t o n
t h e r i n g n i t r o g e n , not the c a r b o x y l a t e c a p , for i t s

counter

transport
17 The c a r r i e r transport nitrogen rate atom, of the proton significantly affects 4). 40 If the proton its counter-

(Figure as in

i s c a r r i e d on the
c r o w n s , the z w i t t e r i o n i c f orm i s

continually

raaintained
and d i f f u s i o n of the crown (proton-coraplexed
o r raeta 1-complexed) w i l l be a t a c o n s t a n t r a t e from one aqueous s i d e to the other. However, i f , as in the c o n v e n t i o n a l - t y p e crown e t h e r
c a r b o x y l i c a c i d s , the z w i t t e r i o n i c form e x i s t s only when the crown i s complexed with a m e t a l , then d i f f u s i o n of the proton-complex from the acidic aqueous has aqueous interfaceacross the organic i n t e r i o r to the b a s i c
i n t e r f a c e w i l l be at a s i g n i f i c a n t l y slower r a t e s i n c e i t 1 ipoph i 1 i c i t y. I n a d d i t i o n , the diaza crowns formed '

reduced

cation-crown
c o m p l e x e s a t a n e u t r a l pH (pH = 6. , F i g u r e 3 ) ,
w h e r e a s the c o n v e n t i o n a l - t y p e crown e t h e r c a r b o x y l i c a c i d s must be in raoderately basic raedia.

COO^ NH

ACIDIC

AQUEOUS

ORGANIC

INTERIOR

AL'EOUS

Figure 4.

A Schematic Representation of Cation Transport by an Azacrown Versus a Crown
18 The d i a z a the crown a, ether b, crown c a r b o x y l i c a c i d s ( v i d e supra) are s i m i l a r to a c i d s prepared by Cram and by Bartsch complexes a r e in t h e i r

carboxylic c).

(series
The c a t i o n - c r o w n
zwitterionic groups, which

forms, are in

e n a b l i n g the i o n i z a b l e c a r b o x y l i c acid
c l o s e proximity to the crown r i n g , to act as The s i g n i f i c a n t d i f f e r e n c e between them i s atom i n t o the crown r i n g which release and the r a t e of
" i n t e r n a l " counteranions. the i n c o r por a t ion affects of the

a nitrogen rate of

markedly
c o u n t e r t r a n s p o r t of the p r o t o n.
Statement of Research Goals Crown e t h e r s have c u r r e n t a p p l i c a t i o n s and f u t u r e for (2) tic use as: possibilities
(1) v e h i c l e s in s e l e c t i v e ion e x t r a c t i o n i n t o s o l v e n t s , raechanisand

r e a g e n t s in p h a s e - t r a n s f e r c h e m i s t r y , (3) s y n t h e t i c and models in a c t i v e ion t r a n s p o r t a c r o s s b i o l o g i c a l

raerabranes,

(4) p o t e n t i a l d r u g s. To c o n t i n u e the search for h i g h l y s e l e c t i v e and e f f i c i e n t ion coraplexing acids raetal
a g e n t s , a new s e r i e s of l i p o p h i l i c crown e t h e r c a r w i l l be s y n t h e s i z e d. This s e r i e s involves the i n c l u p o l y e t h e r r i n g s i z e s to

boxylic sion of

a n i t r o g e n atom i n t o t h r e e d i f f e r e n t
study i t s a f f e c t Although synthetic in to that the it
on cation-complex s t a b i l i t y and s e l e c t i v i t y. this series has s i g n i f i c a n t d i f f e r e n c e s in both the
a p p r o a c h to an i o n i z a b l e , l i p o p h i l i c f u n c t i o n a l group and eraploys a monoaza crown, i t b e a r s a c e r t a i n (c) crown carboxylic acids. relationship

series

Both s e r i e s have an

ionizable

l i p o p h i l i c f u n c t i o n a l group in c l o s e proxiraity to a crown
19 ring. Furthermore, of the major s y n t h e t i c r e a c t i o n of each i s the ionizable

coupling

a s y n t h e t i c i n t e r m e d i a t e c o n t a i n i n g a pendant
group with a crown e t h e r. Three purposes will be addressed in designing the l i p o p h i l i c (1) to provide
monoaza crown e t h e r s and in p l a n n i n g t h e i r s y n t h e s i s : sufficient the o r g a n i c functional agent in
l i p o p h i l i c i t y so t h a t the complexing agent w i l l remain in phase during raetal ion extraction; (2) to provide a
group which w i l l enable f a c i l e d e t e c t i o n of the coraplexing an o r g a n i c p h a s e ; and (3) to provide a pendant ionizable
acid group w i t h i n c l o s e proximity to the azacrown r i n g so
as to i n c r e a s e coraplex s t a b i l i t y. The s y n t h e t i c ionizable crown synthetic and s t r a t e g y will include: (1) p r e p a r a t i o n of the

(i.e., product

i n 98% y i e l d. chloride then 62^ and a c a t a l y t i c amount of used to anhydrous

64 w a s

a l k y l a t e o - x y l e n e 63 u s i n g

o u e o

II u C u z. ^ -J

u <U

03 C H M O r-l
25 the was high procedure shown yield to of be Nightengale. clean, (The 43 From t h e GC a n a l y s i s raonoalkylated for the the reaction in
g i v i n g only the reported

product ^

(88%).

yield )

a l k y l a t i o n of
o - x y l e n e w i t h j t - b u t y l c h l o r i d e was 70%. Nightengale buty 1-benzene butylbenzoic product, and 71 acid did 43 by reported the the

o x i d a t i o n of in

1,2-dimethyl-4-_t2-raethyl-4-_t-

raethod

E q u a t i o n 18 to She

73 in not

34% y i e l d.
r e p o r t e d o n l y t h e one

report

f o r m a t i o n of e i t h e r t h e m o n o o x i d a t i o n

Py. H^o

J i ^X^

t-Bu^\^CH,

* 80^, 6 h

"CHi

isomer,
2-me t h y l-5-_t-butyIbenzoic phthalic acid. 46 ) (The
a c i d , or t h e d i o x i d a t i o n

product, is

4-_^-butyI inert
t e r t i a r y a l k y l group ( _ t - b u t y l )
t o o x i d a t i o n by KMnO,. In the by synthesis
4 ( 5 ) - ( l , 1-dimethyldecyl )-2-methylbenzoic i t was d e t e r m i n e d t h a t GC identify the oxidation the
N igh t enga 1 e ' s p r o c e d u r e , not be directly used to
analysis products gas the

could of

6_5_ s i n c e
t h e c a r b o x y l i c a c i d s would not e l u t e from
chromatograph. yield in of an

Therefore, effort

to d e t e r m i n e t h e t y p e of o x i d a t i o n and condirions, to t h e
to a c h i e v e t h e optimum r e a c t i o n acid

conversion

(or diacid bv-product)

methyl

was n e c e s s a r y.
Gas chromatography then i d e n t i f i e d
type of o x i d a t i o n product (mono-, mono-, d i - ) and the product r a t i o. Second, very used. easily After o ver-ox ida t ion if of 65 t o the d i a c i d can be achieved t o o long of a r e a c t i o n time is

30 In the general by the synthesis, procedure d i t o s y I a t es 83^, , and 85 were (Equation
synthesized 18). the 95%,
o f Dale and K r i s t i a n s e n ^ ^
2_-Toluenesulfonyl glycols 74%, 7_9_, 8 ^ , and

chloride 8J^ a t 5C

i n p y r i d i n e was added s l o w l y to to give the ditosylates in the

and of the

43% y i e l d s ,
respectively. 8_6_ w i t h
E q u a t i o n 19 i n d i c a t e s in t - b u t y l addition

reaction to form

di e thano 1amine dialkoxide 8_3_, 8_4^, ethers and

sodium ^ by the

alcohol of the
8_8_ f o l l o w e d 8_5_ d i s s o l v e d separated
ditosylates raonoaza distilled
in p_-dioxane. by extraction,
The c r u d e t h e n vacuum
t o p r o d u c e t h e p u r e compounds. distillation, a sraall araount all three raonoaza c r o w n s 76_, 2Z> ^^^

After 78 , 1.18 showed

of i m p u r i t y i n t h e N R s p e c t r u m between M glycol or

and 1.20 ppm. ether,

The i r a p u r i t y a p p e a r s to be t h e t r i e t h y l e n e tetraethylene glycol di-^-butyl

di-_t_-butyl

ether,
pen t ae t h y 1 ene the ^-butoxide has of
g l y c o l d i - _ t - b u t y l e t h e r which was forraed by a t t a c k of anion also on the corresponding the glycol glycol ditosylate.
Okahara Reraoval was n o t

reported

as b y - p r o d u c t s.
sraall araounts of i r a p u r i t i e s frora t h e raonaza crowns

atterapted.

C o u p l i n g of t h e L i p o p h i l i c , l o n i z a b l e S y n t h e t i c I n t e r m e d i a t e w i t h t h e Monoaza Crown E t h e r s Compounds reaction 76 , by 77 , of 78 the 8_9_, 0[.> ^ ^ ^.2J_ ^ e r e prepared by the coupling

brominated 3,

e s t e r 56^ w i t h t h e monoaza crown e t h e r s 20). The c o u p l i n g was effected

(Scheme in

Equation

acetonitrile

in t h e p r e s e n c e of sodiura c a r b o n a t e.
31 Scheme 3. Coupling of the Lipophilic, lonizable Synthetic Intermediate with the Monoaza Crown Ethers.

76, n=I 77, n=2 78^, n=3

92 CH^CN, Na^CO^ refliuc, 3 days (20)

CH,^;;;V^COOM

89^, n=l 90, n2 91, n=3

^^"'^-iOC

a^O, rfliui 9 j%
^""'E""

92_, n=l

89, n=l 90^, n=2 91, n=3

22, n=2

94, n=3
32 Purification afforded the of the crude product o i l s by column c h r o m a t o g r a p h y products 8_9^, 2iL> ^nd 91 in

Model-3700 and mm

gas c h r o r a a t o g r a p h e q u i p p e d w i t h a FID d e t e c t o r The column used was a 0.20 SE-30 column from SGE from

temperature X 25 ra

programming c a p a b i l i t y. silica capillary

vitreous the

Corporation; 4 C per m m u t e.

column

t e m p e r a t u r e was 100-250 C i n c r e a s i n g
36 Thin Alumina with layer chroraatography (TLC) was done using e i t h e r Analtech The p l a t e s were precoated Column chroraatography was Scientific

GF o r

S i l i c a GF prepared p l a t e s. gel or alumina.

250 pm s i l i c a

performed
u s i n g e i t h e r alumina (80-200 raesh) from F i s h e r
or s i l i c a gel (40-140 mesh) o b t a i n e d from J. T. Baker Cheraical Co. Eleraental analyses were d o n e by G a l b r a i t h L a b o r a t o r i e s of
K n o x v i l l e , Tennessee. 2-Methy1-2-undecano1 bottoraed funnel, stirrer. the flask, flask was (61). with A 1-L, three-necked, roundaddition raechanical

equipped

a pressure-equalizing

a reflux

c o n d e n s e r with n i t r o g e n a d a p t e r , and a

Magnesium

t u r n i n g s 2. (110 g, 0.452 raol) were placed in
a drying tube was s u b s t i t u t e d i n t o the c e n t e r neck for the s t i r r e r , and then the r e a c t i o n f l a s k was gently flamed for A f t r the m o i s t u r e had been d i s p l a c e d by flaming, the

raechanical

3-5 m i n u t e s. raechanical flushed
s t i r r e r was quickly r e p l a c e d , and the r e a c t i o n flask was well with dry nitrogen. When the f l a s k had cooled to room g, 0.473 raol), d i s s o l v e d in
temperature, fresh, funnel. to the

iodoraethane

5_L ( 6 7. 1
a n h y d r o u s d i e t h y l e t h e r (175 raL), was placed in the a d d i t i o n A small reaction amount of t h i s s o l u t i o n ( c a. 10 mL) was then added f l a s k and s t i r r i n g was begun. as evidenced The r e a c t i o n started

almost reaction then

iraraediately raixture.
by an e f f e r v e s c e n t

and grayish

Addition of the remaining iodoraethane s o l u t i o n was raixture refluxed
a n d m a i n t a i n e d at such a r a t e t h a t the

gently. the

Reflux was continued for 15-30 minutes a f t e r the a d d i t i o n of ether s o l u t i o n had been corapleted. The

iodoraethane/diethyl

37 reaction of ethyl flask was t h e n p l a c e d i n a c o l d w a t e r b a t h , and a s o l u t i o n anhydrous diethyl refluxed reaction
c a p r a t e 6 ( 4 3. 1 g, 0. 5 mol) in f r e s h , mL) was added
a t such a r a t e t h a t t h e m i x t u r e the grayish

gently. mixture placed

Upon c o m p l e t i o n of t h e e s t e r a d d i t i o n , was refluxed in an was The clear had f o r an a d d i t i o n a l h o u r. and a
The r e a c t i o n f l a s k was

ice-bath,

s a t u r a t e d aqueous amraonium c h l o r i d e to e f f e c t a
solution reflux. finally solution
a d d e d d r o p w i s e t h r o u g h t h e a d d i t i o n funnel grayish after been
s o l u t i o n became c l o u d y , t h e n opaque w h i t e , and sufficient The s a t u r a t e d aqueous ammonium c h l o r i d e r e a c t i o n m i x t u r e was s t i r r e d After s e t t l i n g , the organic well layer

added.

(mechanically) was with decanted
f o r 15-20 m i n u t e s. into a 1-L
s e p a r a t o r y funnel and washed

successively

saturated
a q u e o u s amraoniura c h l o r i d e , water. It
s a t u r a t e d aqueous sodium raagnesium sulfate and
bicarbonate, evaporated solution in

was d r i e d over

vacuo then
to a c l o u d y , p a l e y e l l o w s o l u t i o n.

The yellow solution

refluxed
in 5% aqueous sodium h y d r o x i d e m i x t u r e was t r a n s f e r r e d

overnight. funnel and

reaction
to a s e p a r a t o r y grayish,

allowed

t o s e p a r a t e i n t o two l a y e r s : colorless, top l a y e r.

a cloudy,

b o t t o r a l a y e r and a c l e a r , separated with dried then of

The bottom l a y e r was

and e x t r a c t e d w i t h d i e t h y l e t h e r. The r e s u l t i n g e t h e r - s o l u b l e raagnesiura sulfate.
The top l a y e r was washed

water. with vacuum

f r a c t i o n s were corabined and solvent,
R o t a r y e v a p o r a t i o n of the

distiUation 6_1_ a s

( 7 2. 5 - C / 0. mm) a f f o r d e d colorless liquid: 5)

( 3 6. 9 g, 92%) )

alcohol 1143

a clear,

IR Cneat, cm (m, 1-66

(C-0);

^H NMR ( C D C I 3 , (m, 22 H,

0.57-0.97

3 H, (s.

CH2CJL3),

0.97-1.63
( C H ^ ) gC ( CH3 ) ^ ) ,
38 IH, OH). Elemental Found: Analysis. C a l c u l a t e d for C H 0: C 77.35-

H, 1 4. 0 6.

C, 7 7. ; H, 1 3. 8 9.
2-Methyl-2-undecyl H. C. Brown 44 for used. the
The g e n e r a l p r o c e d u r e by their
c o n v e r s i o n of t e r t i a r y a l c o h o l s i n t o

chlorides was the

I n t h i s p r o c e d u r e , anhydrous hydrogen in the a p p a r a t u s i l l u s t r a t e d

generated reaction acid.

in situ, of
in F i g u r e 5, by concentrated
h y d r o c h l o r i c acid with

sulfuric The

apparatus

assembled

tight. buret, fitted,

Concentrated and

hydrochloric sulfuric flask. in
a c i d was p l a c e d i n t o t h e g r a d u a t e d a c i d was p l a c e d i n t o t h e s p e c i a l l y
500-raL E r l e n r a e y e r coluran of raercury drop
The a c i d i n t h e b u r e t was s u p p o r t e d by a An i n t e r n a l caused
the s p e c i a l l y adapted buret t i p.

pressure the seal

o f a p p r o x i m a t e l y 10 t o 20 m below a t m o s p h e r i c m hydrochloric
concentrated of the buret
a c i d to be drawn t h r o u g h the mercury
a n d t o drop i n t o t h e s t i r r e d E r l e n m e y e r f l a s k of acid. T h i s caused t h e g e n e r a t i o n of hydrogen (A c l o u d y , white is
concentrated chloride gas
i n r e s p o n s e to r e s t o r e t h e p r e s s u r e.
v a p o r was e v i d e n c e of a n h y d r o u s HCl f o r r a a t i o n. ) caused by the injection of the alcohol

The p r e s s u r e drop

into the r e a c t i o n

flask.

Therefore, which buret. was

injection

of t h e a l c o h o l 62^ (10 raL, 8.2 g) was a t a r a t e the

enabled

a d r o p w i s e a d d i t i o n of t h e h y d r o c h l o r i c a c i d from the
F o l l o w i n g c o m p l e t i o n of a d d i t i o n of t h e a l c o h o l , for an a d d i t i o n a l

reaction A

continued with vigorous s t i r r i n g change frora a c l e a r , colorless

15 m i n u t e s.

to a c l o u d y , y e l l o w i s h

solution

39 was evident. The reaction s o l u t i o n was reraoved from t h e reaction
w i t h a s y r i n g e and p l a c e d i n t o a s e p a r a t o r y f u n n e l. top layer was r e m o v e d , d i s s o l v e d in m e t h y l e n e filtered,
The c l e a r , chloride,
colorless dried afford 720 with

magnesiura pale

sulfate,
and e v a p o r a t e d i n vacuo to IR ( n e a t , cm~ ) 3 H, CH^CH^ ) ,

yellow liquid 5)

( 8. 0 g, 98%): (m, 8 H,

(C-CI); (ra,

^H NMR ( C D C I 3 , 14 H, CH^ ) ,

0.73-1.07 (m,

1.07-1.50

1.50-1.89

CH^C(CH3)^Cl).

GLC a n a l y s i s :

> 99% p u r i t y ( 1 9. 8 m i n u t e r e t e n t i o n

tirae).

4 - ( l , 1 - D i r a e t h y l d e c y l ) - 1 , 2 - d i r a e thy Ibenzene (65). 63 (198.3 g, 1.867 mol) was weighed directly into

-Xylene a 1-L ,

thr ee-necked , (18.1 an was the g, 0.112
r o u n d - b o 11 omed f l a s k.
Anhydrous f e r r i c c h l o r i d e 6U^ in
m o l ) was a d d e d , and t h e r e a c t i o n f l a s k was p l a c e d

ice-bath. then

2-Me t h y 1 - 2 - u n d e c y 1 c h l o r i d e ^2 ( 7 3. 4 g, 0.358 mol) i n a 250 mL a d d i t i o n f u n n e l and added dropwise when was 0 C. Upon c o r a p l e t i o n of t h e a d d i t i o n , the

placed

raixture
solution stirring reaction resulting
c h a n g e d frora a d a r k brown to a l i g h t brown c o l o r. was continued for an additional 4 h at

Vigorous

0 C, and the The
was t h e n p l a c e d in t h e r e f r i g e r a t o r solution raL) and was poured into The

horaogeneous acid (500

ice-cold, 6 N was then
hydrochloric transferred with

stirred.

t o a 1-L s e p a r a t o r y f u n n e l. ether
The top l a y e r was e x t r a c t e d aqueous
petroleum chloride, well with
( - C ) , t h e n washed w i t h s a t u r a t e d

sodium dried

and w a t e r. calcium mm)
The r e s u l t i n g c l e a r y e l l o w s o l u t i o n was chloride. 87.8 Vacuum d i s t i U a t i o n g (88%) o f 65. a s a (118.5clear.

119.5C/0.05

afforded

(neat,

cm""^) (m , (m,

(CDCl 4 H, (m,

0.66-1.92 3.20-3.83

and and A the

NCH^ ) , 3 H,
3.83-4.21 ether, isoraers for
COOCH3), 7. - 7. showed and only 0.63). H, two

aluraina) (R^ = 0.56

anticipated Calculated
Eleraental A n a l y s i s. 9.91. Found: C,

68.36;

6 8. ; H, 1 0. 0 0. N - [ 4 ( 5 ) - ( l , l - D i r a e t h y l d e c y I ) - 2 - c a r b o r a e t h o x y b e n z y l ]raonoaza-21c rown-7 to the that (91). for 21 This frora c o r a p o u n d was p r e p a r e d , u s i n g a method the similar
b r o m i n a t e d e s t e r _56. ( 2. g, 0.005 m o l ) , 1_8_ ( 1. g, 0.005 m o l ) , and anhydrous g, 0.015 mol). The crude p r o d u c t was

prepared 22

amine (0.80

sodium

carbonate

obtained on two

a s a red-brown o i l. first,
The c r u d e o i l was then chromatographed

colurans:

on s i l i c a g e l u s i n g d i c h l o r o r a e t h a n e : d i e t h y l dichlororaethane:

ether ethyl

( 3 : 1 ) as t h e e l u e n t and t h e n , on aluraina u s i n g acetate ( : ) as t h e e l u e n t oil: IR (neat, to a f f o r d

1.68 g (54%) of 21 ^s H

yellow

cra""^)

1718 (C=0), 1118 ( C - 0 ) ;
48 NMR (CDCl ; (ra, 6) 4 H, 0.58-1.89 NCH^), (m, (ra, 25 H, (m, CH, 29 H, andCH.CH,), OCH^, ArCH^N, alumina)
2.52-292. COOCH3), showed 0.88).

3.05-4.22

6.90-7.81 two

3 H, A r H ). for the

A TLC ( e t h y l a c e t a t e ,
a n t i c i p a t e d isoraers (R Calculated for

= 0.83 and

Eleraental

Analysis.

C,CH,,OQN:
6 7. ; H, 9. 8 6. Found: 6 7. ; H, 9. 8 9.
A General Procedure for the P r e p a r a t i o n of Corapounds 9 2. 9 3. and 94 Af t e r was added coluran to a c h r oma t o g r a p h y of compounds 22. 2> 2i:> ^^ch Water (50

RIOpanel Radiators

RIOpanel

CONTENTS Company introduction BOSS Rio panel radiator introduction Technical data Output tables Dimensions BOSS Rio Aegis LST introduction Technical data Output tables Dimensions BOSS Rio decorative radiator introduction Technical data Output tables BOSS radiator valves Conversion factors Notes BSS branch addresses Mounting Mounting Dimensions

PAGE NUMBER 5

The UKs leading distributor of pipeline and heating solutions, BSS Industrial, offers a comprehensive range of over 60,000 products available from a nationwide branch network of 57 locations. Each BSS branch is stocked with a wide range of products and has their own internal and external sales team as well as a fully merchandised Trade Counter. As well as supplying a wide range of products from leading manufacturers, BSS also offers an own-brand, BOSS, which has a reputation for quality and value founded on almost 100 years of product history. BSS Industrial and RIOpanel, two names synonymous with unbeatable quality and reliability, have joined forces to bring you BOSS RIOpanel Radiators.
RIOpanel is Scandinavias leading radiator manufacturer. Produced in Denmark, the products are subject to the highest possible quality controls, ensuring maximum customer satisfaction. RIOpanel is part of the innovative environmental solutions group Ribe Jernindustri. Founded in 1848, today the group supplies the building services industry with a range of quality products within heating and ventilation. Demonstrating Ribe Jernindustris sustained commitment to European manufacturing, the year-long programme of investment and modernisation has resulted in improved manufacturing processes and new product developments.
RIOpanel manufacture one of the most com-prehensive combinations of heights, depths and lengths of radiators in the industry, offering maximum flexibility in product selection. With the new Aegis low surface temperature system and the stylish Vertical and Horizontal panels RIOpanel now offers one of the largest selections of radiators in Europe.
The BSS Group plc and its subsidiary companies assume no responsibility for typographical errors or omissions or for any misinterpretation of the information provided in this binder. All designs are subject to alteration without notice.
Rio panel radiators BOSS Rio AEGIS LST radiators Rio decorative radiators
The traditional BOSS RIOpanel Standard range is actually a lot more than standard: with a range of 1332 available sizes, in 6 depths and 6 heights, BOSS RIOpanel Standard offers an unsurpassed flexibility. The BOSS RIOpanel Compact is available in the same heights and lengths as the BOSS RIOpanel. The 2 mm steel profiled side panels and top grilles give it an attractive appearance. The BOSS RIOpanel Flat Front is a Scandinavian design classic but is still available in more than 500 sizes. The integrated top, side and front plate create architectural style to complement a modern interior Naturally all BOSS RIOpanels are pressure tested to 13 BAR, with a maximum working pressure of 10 BAR. Each radiator is supplied complete with brackets, air vents and plugs, and in fully recyclable packaging. BOSS RIOpanel are powder coated in white RAL 9010 as standard, but can be supplied in other RAL colours or anti-bacterial paint. Several models can be angled or curved, and all models with feet or special tapping positions. In addition to the numerous standard lengths, RIOpanel can also be delivered in bespoke lengths of 33.3 mm increments.

Please contact your local branch for more information about our special solutions, or chose from the extensive BOSS RIOpanel stock for day to day delivery
BOSS Rio panel radiators BOSS Rio AEGIS LST radiators BOSS Rio decorative radiators
All BOSS RIOpanel radiators are manufactured in Denmark and are subject to ISO 9001 quality control. This ensures a constant standard of materials, dimensions, welding, painting, and pressure testing, and this is why RIOpanel provide a 10 year warranty.
Dimensions - RIOpanel Compact

20SL 20

Dimensions - RIOpanel Flat Front

146 106

203 163

116 76

Dimensions - RIOpanel Standard

Dimensions - continued

Mounting
Standard wall mounting brackets for Standard, Flat front and Compact-ALL HEIGHTS

Dimensions

A B M H N 900 755
Top support bracket with plastic insert

85 - *

135 - *
*For Compact and Flat add 3mm
Radiator support Standard, Compact and Flat Front For heights 255, 355, 455, 555 Types 11, 21, 22, 33
Optional Floor Mounting Brackets
Radiator support MB Standard, Compact and Flat Front For heights 655 and 955 Types 22 and 33
S = From side to centre of the strap S-Measure: Type 11 Other Types Panel length of 400 mm 110 mm 130 mm * Panel length of 500 - 1000 mm 145 mm 160 mm * Panel length of 1100 - 1400 mm 245 mm 260 mm * Panel length of 1500 - 4000 mm 345 mm 360 mm* Number of Bracket Straps Length: 400 - 1700 Length: 1800 - 2600 Length: 2700 - 3600 Length: 3700 - 4000 mm: mm: mm: mm: straps straps straps straps top top top top and and and and bottom bottom bottom bottom
Cover plate dimension: 20.5 x 40.4 mm
*For Compact and Flat add 5mm
Low and High Support from 95-150 mm and 200-320 mm
Low and High Support from 105-150 mm and 180-250 mm
Tappings for Standard, Compact and Flat front

Standard configuration

Optional configuration

Detachable bottom spacer

Technical Data

Height

20SL 11 20SL 11 20SL 11 20SL 11 20SL 11 20SL 33
Water L/m Weight Kg/m n Std. Comp & Flat. Standard Standard 1.5 1.5 2.3 4.2 3.4 5.2 2.5 2.5 4.5 6.3 5.6 8.4 3.5.3.5 6.9.10 14.4 5.1 6.7 9.9 11.5 13.3 19.9.5 13.6 16.28.5 8.8 12.3 17.24.6 36.7 10.7 15.1 21.2 25.6 30.1 44.9 12.5 17.8 24.9 30.2 35.18.1 26.1 35.8 43.4 51.7 77.1 1.38 1.35 1.34 1.38 1.34 1.3 1.29 1.33 1.35 1.31 1.29 1.32 1.3 1.32 1.32 1.3 1.31 1.31 1.31 1.32 1.31 1.3 1.32 1.31 1.32 1.31 1.3 1.31 1.33 1.31 1.34 1.32 1.31 1.37 1.38 1.33
Weight Kg/m Compact 10.3 12.2 14.3 21.17.1 20.17.8 21.6 25.3 37.7 21.6 26.1 30.4 45.4 25.4 30.6 35.6 53.1 36.9 45.1 53.7 81
n Compact 1.31 1.32 1.31 1.31 1.33 1.32 1.32 1.32 1.32 1.32 1.32 1.33 1.31 1.32 1.33 1.33 1.31 1.32 1.33 1.34 1.31 1.32 1.34 1.35
Weight Kg/m Flat front 12.4 14.3 16.4 23.8 16.23.1 32.9 21.5 25.41.4 26.1 30.6 34.9 49.9 30.7 35.9 40.9 58.4 44.6 52.8 61.4 88.7
n Flat front 1.32 1.31 1.34 1.34 1.32 1.31 1.34 1.34 1.32 1.31 1.34 1.34 1.32 1.31 1.34 1.34 1.32 1.31 1.34 1.34 1.32 1.31 1.34 1.34

Pressure Drop

10000.00 1000.00 100.00 10.00 1.00.10.100 1000

Pressure Drop kPa

Flow Rateee l/h
Flow Rate litres per hour

Height 255mm, Standard H

UK Stock sizes
Type 10 Standard Length 4000

Type 11 Standard

Type 20SL Standard

Type 21 Standard

Type 22 Standard

Type 33 Standard

code 60200343 60200354

Watts 950 978

code 60200642 60200653

Watts 952 992

code 60202443

Watts 1889

code 60200985

Watts 1136

code 60201633

Watts 3109

code 60201688

60201762

60201814

60201227

60201932

60200716 60200727

1230 1270

60202037 4553

60200812

60200376 60200387

1034 1062

60200406

Output watts 75/65-20oC
BOSS Rio panel radiators BOSS Rio AEGIS LST radiators BOSSRio decorative radiators
Height 255mm, Compact Height 255 mm, Compact
UK Stock sizes Danish Stock Sizes

UK Stock Sizes

Type 20SL Compact Length 4000 Type 21 Compact Type 22 Compact Type 33 Compact
Height 255mm, Flat Flat Front Height 255 mm, Front
Type 20SL Flat Front Type 21 Flat Front Type 22 Flat Front Type 33 Flat Front

code 60216306

Watts 1851

code 60215082

Watts 2475

code 60215488

Watts 3047

code 60215828

Watts 3793

60225398

60224703

60224939

60225162

60215872 60215883

4239 4350

60215894 4462

Output watts 75/65-20 C
Height 355mm, Standard Height 355 mm, Standard
Type 10 Standard Length 4000 Type 11 Standard Type 20SL Standard Type 21 Standard Type 22 Standard Type 33 Standard

code 60202849

Watts 1481

code 60203264

Watts 2146

code 60204886

Watts 2481

code 60203467 60203478

Watts 1910 1996

code 60203829

Watts 1941

code 60204469

Watts 6181

60203851

60203873

60203969

60203508 60203519

2170 2257

60203541 60203552

2430 2517

60203574 60203585

2691 2778

60203991

60203626 60203637

3125 3212

60204019

60204074

60203659 60203670

3385 3472
Height 355mm, Compact Height 355 mm, Compact
Height 355mm, Flat Flat Front Height 355 mm, Front

code 60217939

Watts 2431

code 60216712

Watts 3403

code 60217127

Watts 4227

code 60217426 60217437

Watts 4543 4694

60226323

60225631

60225856

60226090

60217522 60217533

5906 6057
Height 455mm, Standard Height 455 mm, Standard

code 60205290

Watts 1857

code 60205438 60205449

Watts 1128 1199

code 60207346

Watts 3214

code 60205781 60205792

Watts 1062 1169

code 60206215 60206226

Watts 1581 1712

code 60206931

Watts 7715

60205833

60206292

60205929

60205652

60206311

60206344 60206355

3161 3293

60205951

60206377

60205973

60206429

60206012

60206034 60206045

3612 3718

60206473

60205674 60205685

2609 2679

60206089 60206108

4143 4249

60206503 60206514

5137 5269

60205704 2820
Height 455mm, Compact Height 455 mm, Compact
Height 455mm, Flat Flat Front Height 455 mm, Front

code 60219592

Watts 3150

code 60218033

Watts 1250

code 60218760

Watts 5164

code 60218834

Watts 1890

60227240

60226559

60226784

60227015

60218856 60218867

2269 2457

60218269

60219024 60219035

5104 5293

60219079

60219175

60218343
Height 555mm, Standard Height 555 mm, Standard
Danish Stock Sizes UK Stock Sizes

code 60207689

Watts 2025

code 60207944 60207955

Watts 1820 1911

code 60209638 60209649

Watts 3818

code 60208241 60208252

Watts 1290 1419

code 60208614 60208625

Watts 1314 1478

code 60209383

Watts 9135

60208669

60208274

60208296

60208754

60208337

60208359

60208776 60208787

3614 3778

60207999

60208381

60208411

60208806 60208817

4107 4271

60208016

60208433 60208444

3612 3741

60208861

2821 60208071

60209778 60209789

60208477

60208935 60208946

6078 6242

60208145

60208507

60207719

60208529

60207763

60208551 60208562

5031 5160

60208968 6571

60208156 3640

Height 555mm, Compact Height 555 mm, Compact
Height 555mm, Flat Flat Front Height 555 mm, Front

code 60220879

Watts 936

code 60219795

Watts 2781

code 60220399

Watts 6440

code 60220429

Watts 1343

60228061

60227476

60227709

60227934

60220451 60220462

1790 2014

60220525 60220536

3357 3581

60220975

60228083

60220558 60220569

4029 4252

60228168

60221198

60220643 60220654

5595 5818

60219998

60220676

60220761

60220802 8952

60221217

Height 655mm, Standard Height 655 mm, Standard

code 60209959

Watts 1226

code 60210615

Watts 4245

code 60212235

Watts 4413

code 60210818

Watts 3252

code 60211414

Watts 7533

code 60211809

Watts 9927

60210209

60210958 60210969

5174 5321

60211019

60211831 10449

Height 655mm, Compact Height 655 mm, Compact
UK Stock sizes Sizes Danish Stock
Height 655mm, Flat Flat Front Height 655 mm, Front

code 60222573

Watts 1730

code 60221623

Watts 5795

code 60222027

Watts 7382

code 60222038

Watts 1024

60222071

60228914

60228401

60228637

60228862

60222145

60228936 60228947

1105 1205

60228969

60222167 60222178

4096 4352

60228991

60222595

60229041 60229052

2007 2108

60222241

60222614 60222625

2162 2271

60222776

60229096

60222263

60222296

60222315

60222337 60222348

7936 8192

60222392

60222839

60222411

60222433 10240

Height 955mm, Standard Height 955 mm, Standard

code 60212342 60212353

Watts 1100 1192

code 60212811

Watts 2410

code 60214678

Watts 5989

code 60213281 60213292

Watts 4526 4715

code 60213643

Watts 4847

code 60214143 60214154

Watts 9636 9980

60212619

60212855

60213687

60212877

60213034 60213045

60213794

60213333

5222 5356

60213418 60213429

6978 7166

60214272 13765

60213835

60212641 60212652

3576 3667

60213451

60213857
Height 955mm, Compact Height 955 mm, Compact
Height 955mm, Flat Flat Front Height 955 mm, Front

code 60224396

Watts 4695

code 60222872

Watts 1109

code 60223660

Watts 9501

code 60223671

Watts 1349

60223734 60223745

3372 3710

60229842

60229318

60229554

60229779

60222935

60229897

60223767 60223778

4385 4722

60223029

60223819

60229938

60223852

60229971

60223062 60223073

4251 4435

60223874

60229993

60223915 60223926

8769 9106

60230018 3406

60223191 60223210

6469 6653

60224075 13490

60224437

60224459 60224470

5576 5722

60223254

60224481 5869
The softly contoured front plate and profiled side panels minimise the risk of injury in the event of a fall against the case with smooth rounded corners further enhancing the natural protection the design provides. The curved top prevents items being placed on the top of the case including drinks, food and tissues significantly reducing the associated cleaning costs. Manufactured with durability in mind, the case is constructed from 1.5mm steel with 2mm side panels. Further strength is provided by the stiffening folds in the front panel which add an additional design feature. The casing and radiators are finished in a powder coat white RAL9010 Produced as either floor or wall mounted models the range is available in numerous sizes. Lengths available from 600 mm to 2000 mm and heights from 500 mm to 800 mm in the wall model and, 600 mm to 800 mm in the floor range. To improve the installation time, each unit is supplied with its own full size installation template and all necessary fixings. The template is secured to the wall to allow the fixing holes to be quickly and accurately drilled. Knock outs are provided in the lower quarter of each side panel for surface mounted pipe work to enter the casing. The BOSS Rio AEGIS LST has been designed to work in conjunction with the BOSS thermostatic radiator valves. Knock outs are provided in the end panels to incorporate the BOSS thermostatic radiator valve allowing user adjustment of the room temperature. Where a tamperproof installation is required the BOSS thermostatic radiator valve with remote sensor should be installed.

The BOSS Rio AEGIS LST has been designed to add a stylish look to an otherwise functional device. Designed in accordance with the NHS guidelines the Aegis offers full compliance to all existing standards for Low Surface Temperature devices

Wall mounted

Floor mounted

Wall mounted 1

150 500,600, 700 & 800 mm
600 - 2000 mm / 200 mm increments

600, 700 & 800 mm

Dimensions - BOSS Rio AEGIS LST floor and wall mounted

77.5 177.5

Wall mounted H A B M J P Floor mounted 500
Wall mounted Wall mounted
S = From side to center of the radiator bracket S-Measure: LST length of 600 mm 238,5 mm LST length of 800 - 1200 mm 268,5 mm LST length of 1400 - 1600 mm 368,5 mm LST length of 1800 - 2000 mm 468,5 mm
Number of radiator brackets
Floor mounted Floor mounted

LST length: LST length:

600 - 1800 mm: 2000 mm:
2 straps top and bottom 3 straps top and bottom
Illustration shows wall mounted Aegis and template
11 LST wall 22 LST wall 21 LST wall 11 LST wall
Water l one metre 1.6 3.2 2.0 4.0 4.0
difference per 200 mm - l 0.4 0.8 0.5
Weight Kg one metre 18.5 23.8 22.4
difference per 200 mm - Kg 3.4 4.7

5.3 5.9 3.6 6.7 4.2

21 LST wall 22 LST wall

1.0 1.0 0.4

29.1 32.0 24.9 27.1 19.6

11 LST floor

21 LST floor 11 LST wall 21 LST wall 22 LST wall

22 LST floor

2.4 4.8 4.8

0.6 1.2 1.2

26.4 38.0 34.5

5.1 8.0 7.1

21 LST floor 22 LST floor 21 LST wall 22 LST wall 11 LST wall

2.0 4.0 4.0

1.0 1.0 0.7

21.3 26.5 28.7

3.9 5.2 5.8

5.6 5.6 4.8

1.4 1.4 0.6

39.8 44.1

8.3 9.4 4.7 7.2

21 LST floor

2.4 4.8

25.2 34.8

Example The weight of a complete BOSS Rio Aegis LST type 21 wall monted, 600 high, 1800 long wide is calculated below: Weight of one meter = 29.1 kg Weight of four 200 mm increments of 5.9 kg each = 23.6 kg Total weight = 52.7 kg

Height 500mm, LST LST wall Height 500 mm, wall
Type 11 LST wall Length Type 21 LST wall Type 22 LST wall

code 60230896 60230904

Watts 807 908

code 60230959

Watts 979

code 60231075 60231086

Watts 1622 1825

60230981 60230992

1306 1468
Height 600mm, LST LST wall Height 600 mm, wall
Type 11 LST wall Length 2000 Type 21 LST wall Type 22 LST wall
Height 600mm, LST LST oor Height 600 mm, floor

Type 11 LST oor

Type 21 LST oor Type 22 LST oor

code 60231160 60231171

Watts 1038 1167

code 60231245 60231256

Watts 1564 1759

code 60231341 60231352

Watts 1939 2181

code 60230095 60230103

Watts 798 898

code 60230180 60230191

Watts 1292 1453

code 60230276 60230287

Watts 1604 1805
Height 700mm, LST LST wall Height 700 mm, wall
UK6 Stock sizes Danish Stock Sizes
Height 700mm, LST LST oor Height 700 mm, floor
Type 11 LST oor Type 21 LST oor Type 22 LST oor

code 60231426 60231437

Watts 1369 1540

code 60231511 60231522

Watts 1940 2183

code 60231599 60231607

Watts 2470 2780

code 60230361 60230372

Watts 1072 1206

code 60230446 60230457

Watts 1615 1816

code 60230542 60230553

Watts 2003 2252
Height 800mm, LST LST wall Height 800 mm, wall
Height 800mm, LST LST oor Height 800 mm, floor

code 60231684 60231695

Watts 1613 1815

code 60231769 60231780

Watts 2247 2528

code 60231865 60231876

Watts 2862 3221

code 60230586 60230597

Watts 706 883

code 60230712 60230723

Watts 2002 2252

code 60230808 60230819

Watts 2549 2868

60230638

The Horizontal range is available in up to 8 heights, 8 widths and with or without rear convector fins. Starting at 140 mm heights, the lower models are suitable for mounting at low level as well as high level. The Vertical range is available in 4 heights, up to 7 widths and, as the Horizontal, with or without rear convector fins. Besides being an attractive part of the interior, the vertical design is excellent where wall space is limited. Naturally all BOSS RIOpanel decorative radiators are pressure tested to 13 BAR, with a maximum working pressure of 10 BAR. Each radiator is supplied complete with brackets, air vents and plugs, and in fully recyclable packaging. The BOSS RIOpanel decorative radiators are powder coated in white RAL 9010 as standard, with the discreet metal frame in a complementing grey RAL 7043. However, both Horizontal and Vertical can be supplied in other RAL colours. Please contact your local branch for more information about special colours or other special solutions.

(49341026)

TRV horizontal

Rp 1/2" BS.21

(49341048)
2 m & 8 m remote sensor

(49341081 and 49341229)

100.0 80.0

LOCKED 53.0

UNLOCKED
Head shown for illustration use only
The BOSS radiator valve range consists of 4 manual radiator valves and a choice of up to 24 TRV options The BOSS range of Thermostatic Radiator Valves (TRVs) comprises three different 1/2/ 15mm body patterns angle, reverse angle (axial) and straight with a choice of pre-setting and non presetting options making six valves in all. These bodies are complemented by four different thermal heads, standard, remote sensing and remote adjusting in 2m and 8m capillary lengths. All thermal heads and bodies in the range are compatible with each other and approved to EN 215. The bodies are all approved to EN 215 and other standards e.g. BS EN1254 where EN215 does not specify the connection type. The thermal heads all incorporate range limiting using two plastic pins (supplied) and a handle locking mechanism that prevents movement from the set position. This works by pulling the outer cover to a raised position to unlock and pushing the outer cover to a lower position to lock. Additionally the standard and remote sensing versions can be tamperproofed using a specially designed plastic key in either the locked or unlocked position. As well as the choice of TRV options using separate thermal heads and valve bodies, two TRV head and body packs are available in angle and reverse angle patterns. To complement the range there is a full range of accessories shown with the complete valve range.

BOSS Radiator Valves

53.0 33.8
TRV adaptor for BOSS Rio AEGIS Panel

(49341240)

45.0 EFFECTIVE LENGTH 64.5 MAX 60.1 MIN
Conversion factors K=(t)n 50
The conversion factor k can be calculated from the equation or estimated from the table. t is mean water temperature minus room temperature; n-coefficients are found in the technical date tables.

t 15 10

0.652 0.700

t 41 40

t 50 49

55.5 56

t 58 57

18.0 A/F HEX

M30.0 x 1.5p

M30 x 1.5p

Pipeline & Heating Solutions ABERDEEN Unit 5,South Middleton Base,Greenwell Road, East Tullos,Aberdeen AB12 3AX Tel:Fax:Email:1550.sales@bssgroup.com BELFAST 36-38 Duncrue Road,Duncrue Industrial Estate, Belfast,Northern Ireland BT3 9BP Tel:4000 Fax:4010 Email:1910.sales@bssgroup.com BIRMINGHAM Units 2 & 4 Crystal Drive,Sandwell Business Park, Smethwick,Warley,West Midlands B66 1QG Tel:6000 Fax:5363 Email:1220.sales@bssgroup.com BIRMINGHAM CENTRAL Unit 49,Gravelly Industrial Park, Tyburn Road,Erdington,Birmingham B24 8TG Tel:0370 Fax:2296 Email:1810.sales@bssgroup.com BOREHAMWOOD Chester Road,Borehamwood,Herts WD6 1LT Tel:4100 Fax:4101 Email:1500.sales@bssgroup.com BOURNEMOUTH Unit 3B,Broom Road Business Park, Broom Road,Poole,Dorset BH12 4PA Tel:Fax:Email:1400.sales@bssgroup.com BRENTFORD Transport Avenue,Great West Road, Brentford,Middlesex TW8 9HF Tel:2727 Fax:2730 Email:1110.sales@bssgroup.com BRISTOL Albert Road,St Philips,Bristol BS2 0BS Tel:7900 Fax:7901 Email:1250.sales@bssgroup.com CAMBRIDGE Unit 3,Rosemary Lane,Cambridge CB1 3LQ Tel:Fax:Email:1840.sales@bssgroup.com CARDIFF Unit 4,Trident Park,Glass Avenue,Ocean Way, Cardiff CF24 5EN Tel:2400 Fax:7815 Email:1280.sales@bssgroup.com CARLISLE Unit 2A,Port Road Business Park,Carlisle CA2 7AJ Tel:Fax:Email:1780.sales@bssgroup.com CHESSINGTON Oakcroft Road,Chessington Industrial Estate, Chessington,Surrey KT9 1RH Tel:3800 Fax:5241 Email:1950.sales@bssgroup.com COLCHESTER Unit 6,Smeaton Close,Severalls Industrial Park Colchester,Essex CO4 9QY Tel:Fax:Email:1200.sales@bssgroup.com CORK Unit 20,South Link Park,Ballycurren Road,Grange,Cork Tel:321588 Fax:321595 Email:1960.sales@bssgroup.com COVENTRY Unit 17,Torrington Avenue,Coventry, West Midlands CV4 9HN Tel:4744 Fax:0574 Email:1490.sales@bssgroup.com CRAWLEY 12A Denvale Trade Park,Haslett Avenue East, Crawley RH10 1SS Tel:Fax:Email:1390.sales@bssgroup.com CROYDON Unit 34,Factory Lane,Croydon,Surrey CR0 3RL Tel:2300 Fax:6142 Email:1120.sales@bssgroup.com DARTFORD Unit 11 Orbital One,Green Street,Green Road, Dartford,Kent DA1 1QG Tel:Fax:Email:1570.sales@bssgroup.com DERBY Riverside Road,Pride Park,Derby DE24 8HH Tel:Fax:Email:1450.sales@bssgroup.com DUBLIN White Heather Industrial Estate, 301 South Circular Road,Dublin 8 Tel:165100 Fax:165165 Email:1930.sales@bssgroup.com

BSS BRANCH LOCATIONS THROUGHOUT THE UK & IRELAND
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Registered Office:The BSS Group plc, Fleet House,Lee Circle,Leicester LE1 3QQ,Registered in England Number:60987 Tel:3232 Fax:1343 E-mail:reception@bssgroup.com Web:www.bssuk.co.uk

BOSSRio/1208/5000