Curriculum Vitae
Lars Peter Gr ner Hanson, December, 2010 u
Address, work: Danish Research Center for Magnetic Resonance Dept.340, Copenhagen University Hospital Hvidovre DK-2650 Hvidovre, Denmark Phone: (+45) 3632 3326, Fax: (+45) www: http://www.drcmr.dk/ e-mail: larsh@drcmr.dk and DTU Electro, Bldg. 349 Technical University of Denmark DK-2800 Kgs. Lyngby Phone: (+45) www: http://www.elektro.dtu.dk/ Address, home: Asnsgade 1, st.th. DK-2200 Kbenhavn N Mobile: (+45) Owner of company: http://www.mriware.com/
Degrees M.Sc., Physics. Minors: Math and computer science. University of Copenhagen, 1995. Ph.D., Chemistry. University of Copenhagen, 2000. Experience Feb 69 Sep 88 Aug 93 - Feb 94 Feb 94 - May 95 Jul 95 Oct 95 - Jan 96 Feb 96 - Aug 96 Oct 96 - Oct 99 Oct 98 - Apr 99 Oct 99 - Oct 00 Feb 00 Oct 00 - Oct 06 Oct 02 - May 03 Nov 06 - present Mar 08 - present Oct 09 - present Born in Denmark. Matriculated at University of Copenhagen. Conscription. Diploma work. Max-Planck-Institut f r Quantenoptik, Garching, Germany. u M.Sc. Physics. Minors: Math and computer science. Promotion stipend. Max-Planck-Institut f r Quantenoptik. u Introductory stipend, DRCMR, Hvidovre Hospital Ph.D. study, University of Copenhagen. Visiting Ph.D. student Lucas MR Center, Stanford University, California. Post doc, DRCMR, Hvidovre Hospital. Ph.D. Chemistry, University of Copenhagen. Chief physicist. DRCMR, Hvidovre Hospital. Research Management Course (CBS on behalf of Rektorkollegiet). Senior Researcher and Group Leader (Physics and Acquisition). DRCMR, Hvidovre Hospital. Board member and secretary for the Danish Society for Magnetic Resonance in Medicine. Associate Professor at the Technical University of Denmark.
Awards Oct. 2009: The European Society for Magnetic Resonance in Medicine and Biologys Info-RESO Award for software available at http://www.drcmr.dk/bloch
Publications Reports L. G. Hanson, Wave packet dynamics in two-electron atoms; Inuence of a strongly driven core resonance (1995), diploma work. Supervisors: N. O. Andersen (University of Copenhagen) and P. Lambropoulos (Max-Planck-Institut f r Quantenoptik). u L. G. Hanson, Fast volumetric magnetic resonance spectroscopic imaging; Methodological developments for echo planar spectroscopy (2000), thesis. Supervisors: K. Schaumburg and O. B. Paulson (University of Copenhagen). Papers in refereed journals L. G. Hanson, J. Zhang and P. Lambropoulos, Theory of core-resonant ionization, Euro Phys Lett, 30(2), 81-86 (1995). L. G. Hanson and P. Lambropoulos, Non-dispersing wave packets in two-electron atoms; atomic mode-locking by loss-modulation, Phys Rev Lett, 74, 5009-12 (1995). L. G. Hanson, J. Zhang and P. Lambropoulos, Manifestations of atomic and core resonances in photoelectron energy spectra, Phys Rev A,55, 2232-44 (1997) L. G. Hanson, K. Schaumburg and O. B. Paulson, Reconstruction strategy for echo planar spectroscopy and its application to partially undersampled imaging, Magn Reson Med, 44, 412-17 (2000). http://www.drcmr.dk:8080/19/. L. G. Hanson, E. Adalsteinsson, A. Pfefferbaum and D. M. Spielman, Optimal voxel size for measuring global gray and white matter proton metabolite concentrations using chemical shift imaging, Magn Reson Med, 44, 10-18 (2000). http://www.drcmr.dk:8080/20/. T. N. Sager, S. Topp, L. Torup, L. G. Hanson, B. Egestad and A. Mller, Evaluation of CA1 damage using single-voxel 1H-MRS and un-biased stereology: Can non-invasive measures of N-acetylasparate following global ischemia be used as a reliable measure of neuronal damage? Brain Res, 892, 166-75 (2000). I. K. Andersen, A. Szymkowiak, C. E. Rasmussen, L. G. Hanson, J. Marstrand and L. K. Hansen, Perfusion quantication using Gaussian process deconvolution, Magn Reson Med, 48, 351-61 (2002). A. P. Born, I. Law, T. E. Lund, E. Rostrup, L. G. Hanson, G. Wildschidtz, H. C. Lou and O. B. Paulson, Cortical deactivation induced by visual stimulation in human slow-wave sleep, Neuroimage, 17(3), 1325-35 (2002). H. K. Mathiesen, T. Tscherning, P. S. Srensen, H. B. W. Larsson, E. Rostrup, O. B. Paulson, and L. G. Hanson, Multi-slice echo planar spectroscopic MR imaging provides both global and local metabolite measures in multiple sclerosis, Magn Reson Med, 53, 750-59 (2004). T. Stavngaard, L. V. Sgaard, J. Mortensen, L. G. Hanson, J. Schmideskamp, A. K. Berthelsen and A. Dirksen, Hyperpolarised 3 He MRI and 81m Kr SPECT in chronic obstructive pulmonary disease, Eur J Nucl Med Mol Imaging, 32, 448-57 (2005). H. K. Mathiesen, A. S. Nielsen, K. Nielsen and L. G. Hanson, MR-spektroskopi til vurdering af kognitive forstyrrelser, Ugeskr Laeger, 168, 357-59 (2006). H. K. Mathiesen, A. Jnsson, T. Tscherning, L. G. Hanson, J. Andresen, M. Blinkenberg, O. B. Paulson and P. S. Srensen, Correlation of global N-acetyl aspartate with cognitive impairment in multiple sclerosis, Arch Neurol, 63, 533-36 (2006). P. S. Srensen, A. Jnsson, H. K. Mathiesen, M. Blinkenberg, J. Andresen, L. G. Hanson and M. Ravnborg, The relationship between MRI and PET changes and cognitive disturbances in MS, J Neurol Sci, 245, 99-102 (2006). K. Nielsen, E. Rostrup, J. L. Frederiksen, S. Knudsen, H. K. Mathiesen, L. G. Hanson and O. B. Paulson, Magnetic Resonance Imaging at 3.0 Tesla Detects More Lesions in Acute Optic Neuritis Than at 1.5 Tesla, Invest Radiol, 41, 76-82 (2006). L. G. Hanson, T. E. Lund and C. G. Hanson, Encoding of electrophysiology and other signals in MR images, J Magn Reson Imag, 25, 1059-66 (2007). http://www.drcmr.dk:8080/18/. L. G. Hanson, A graphical simulator for teaching basic and advanced MRI techniques, RadioGraphics, 27(6):e27, 2007. Software available at http://www.drcmr.dk/bloch.

L. G. Hanson, Is Quantum Mechanics necessary for understanding Magnetic Resonance? Concepts in Magn Reson, 32A(5), 329-40 (2008). http://www.drcmr.dk:8080/22/. R. de Nijs, M. J. Miranda, L. K. Hansen and L. G. Hanson, Motion correction of Single Voxel Spectroscopy by Independent Component Analysis applied to spectra from non-anesthetized pediatric subjects , Magn Reson Med, 62, 1147-1154 (2009). C. Dali, L. G. Hanson, N. Barton, J. Fogh, N. Nair and A. M. Lund, Brain N-acetylaspartate levels correlate with motor function in metachromatic leukodystrophy, Neurology, 75, 1896903 (2010). Patents L. G. Hanson, T. E. Lund and C. G. Hanson, Encoding and transmission of signals as RF signals for detection using an MR apparatus, PCT/DK2005/000343, WO/2005/116676 (pending), 2005. Longer conference papers L. G. Hanson and P. Lambropoulos, Wave packet dynamics in two-electron atoms; Inuence of a strongly driven core resonance, NATO ASI Series: Proceedings of SILAP IV (1995), Kluwer Academic Publishers, Amsterdam. P. Willendrup, C. Svarer, L. G. Hanson and O. B. Paulson, A simple approach to combined inhomogeneity correction and tissue segmentation, in Brain imaging using PET, In: Senda M, Kimura Y, Herscovitch P (eds). Brain imaging using PET, Academic Press, 159-62 (2002). R. Engholm, A. Dubinskiy, R. Larsen, L. G. Hanson and B. Christoffersen, Proceedings of the SPIE, 6144, 1228-38 (2006). Unrefereed publications L. G. Hanson, J. Zhang and P. Lambropoulos, Comment on Observation of Continuum-Continuum Autler-Townes Splitting, Phys Rev Lett,77(1), 202 (1996). L. G. Hanson, MR-skanning: Billeder fra den forbudte side af blgelngdegrnsen, GAMMA Tidsskrift for fysik 143, p. 8-26, 2006. http://www.drcmr.dk:8080/21/. L. G. Hanson, Bloch simulator and viewer, Educational software for illustrating basic phenomena involved in magnetic resonance imaging. http://www.drcmr.dk/bloch, 2007 L. G. Hanson, Introduktion til teknikken bag MR-skanning, Introduction to MRI in Danish, http://www.drcmr.dk/Intro.pdf, 44 pages, revised 2009. L. G. Hanson, Introduction to Magnetic Resonance Imaging Techniques, Educational material for technical and non-technical students, http://www.drcmr.dk:8080/37/, translation by Theis Groth, 48 pages, 2009. J. E. Wilhjelm, J. Henriksen and L. G. Hanson, En MR-skanner man kan lege med, MTI - Medicinsk Teknologi og Informatik, 6(6), p. 10-12, 2009. L. G. Hanson, MR-skanning ved 7 tesla feltstyrke etableres i Danmark, MTI Medicinsk Teknologi&Informatik, 7(4), p. 20-22, 2010. Abstracts (single page contributions to conference proceedings) L. G. Hanson, S. Topp and O. B. Paulson, Correction for B1 inhomogeneity using EPI-based eld maps, in Proc. of the ISMRM 6th Annual Meeting, 128 (1998) L. G. Hanson and O. B. Paulson, Segmented Spectroscopy: A exible alternative to single voxel methods, in Proc. of the ISMRM 6th Annual Meeting, p. 363 (1998) L. G. Hanson, K. Schaumburg and O. B. Paulson, A reconstruction strategy for echo planar spectroscopy, in Proc. of the ISMRM 7th Annual Meeting, p. 682, 1999. E. Adalsteinsson, L. G. Hanson, C. H. Meyer and D. M. Spielman, Incorporation of T2 measurements in volumetric CSI, in Proc. of the ISMRM 7th Annual Meeting, 250, 1999. L. G. Hanson, Lipid containment achieved for echo planar spectroscopic imaging by modulation of the readout-gradient envelope, in Proc. of the ISMRM 8th Annual Meeting, 373, 2000. A. P. Born, T. E. Lund, L. G. Hanson, A. Steensgaard, P. L. Madsen, E. Rostrup, and H. C. Lou, Negative visually induced BOLD response during human adult slow-wave sleep, in Proc. of the ISMRM 8th Annual Meeting, 498, 2000.

T. E. Lund and L. G. Hanson, Physiological noise reduction in fMRI using vessel time series as covariates in a general linear model, in Proc. of the ISMRM 9th Annual Meeting, 22, 2001. L. G. Hanson, J. Marstrand and E. Rostrup, Use of training data for improved model-free estimation of the impulse response in dynamic MRI, in Proc. of the ISMRM 9th Annual Meeting, 1583, 2001. L. G. Hanson, E. Kalowska and E. Rostrup, Improving perfusion quantication in stroke by principal component ltering, Proc. of the ISMRM 10th Annual Meeting, 1086, 2002. I. K. Andersen, S. Rosenbaum, K. Sidaros, L. G. Hanson and H. B. W. Larsson, Improved Brain Perfusion Quantication using a Saturation Recovery Sequence, Proc. of the ISMRM 10th Annual Meeting, 590, 2002. L. G. Hanson and T. Dyrby, RF inhomogeneity correction: Validity of the smooth-bias approximation, Proc. of the ISMRM 10th Annual Meeting, 2316, 2002. A. Skimminge, K. Markenroth, L. G. Hanson, Improved spectroscopy using cluster analysis and lipid signals as a motion indicator, Proc. of the ISMRM 11th Annual Meeting, 269, 2002. H. K. Mathiesen, T. Tscherning, P. S. Srensen, O. B. Paulson and L. G. Hanson, Multi-slice echo planar spectroscopic imaging in multiple sclerosis, Proc. of the ISMRM 11th Annual Meeting, 2519, 2003. I. K. Andersen, S. Rosenbaum, K. Sidaros, L. G. Hanson and H. B. W. Larsson, T1 Based Brain Perfusion Quantication, Proc. of the ISMRM 11th Annual Meeting, 2197, 2003. M. J. Miranda, L. C. Srensen, A. P. Born, A.-M. Leffers, B. Peitersen and L. G. Hanson, Multislice echo planar MR spectroscopic imaging (EPSI) in premature infants at term-equivalent age, Proc. of the ISMRM 11th Annual Meeting, 2107, 2003. H. K. Mathiesen, T. Tscherning, P. S. Srensen, O. B. Paulson and L. G. Hanson, Multi-slice echo planar spectroscopic imaging measures pathology in cerebral cortex in multiple sclerosis, Proc. of the ISMRM 12th Annual Meeting, 530, 2004. E. Rostrup, M. Liptrott, K. Nielsen and L. G. Hanson, Anisotropy of the BOLD Response, Proc. of the ISMRM 12th Annual Meeting, 1022, 2004. T. Stavngaard, L. V. Sgaard, L. G. Hanson and J. Mortensen, Comparison of hyperpolarized 3 He MR imaging and Krypton scintigraphy in healthy volunteers and COPD patients, Proc. of the ISMRM 12th Annual Meeting, 1672, 2004. K. Sidaros, I. K. Andersen and L. G. Hanson, Accurate B1 -insensitive fast T1 -measurements at 3T, Proc. of the ISMRM 13th Annual Meeting, 2188, 2005. L. G. Hanson, T. E. Lund and C. G. Hanson, The MFAMOUS technique: Electrophysiological signal recording by MR image acquisition, Proc. of the ISMRM 13th Annual Meeting, 1526, 2005. L. G. Hanson, H. Lund and E. Rostrup, Efcient multi-dimensional diffusion measurements at 3 Tesla, Proc. of the ISMRM 13th Annual Meeting, 1298, 2005. K. Nielsen, E. Rostrup, J. L. Frederiksen, S. Knudsen, H. K. Mathiesen, L. G. Hanson, O. B. Paulson, Magnetic resonance imaging at 3.0 tesla detects more lesions in acute optic neuritis than at 1.5 tesla, Proc. of the ISMRM 13th Annual Meeting, 1051, 2005. H. K. Mathiesen, T. Tscherning, A. Jnsson, J. Andresen, P. S. Srensen, M. Blinkenberg, E. Rostrup, O. B. Paulson, L. G. Hanson, Global NAA/Cr measured by multi-slice echo planar spectroscopic imaging correlates with cognitive impairment in multiple sclerosis, Proc. of the ISMRM 13th Annual Meeting, 1054, 2005. L. G. Hanson, T. E. Lund, C. G. Hanson, The MFAMOUS technique: Electrophysiological signal recording by MR image acquisition Neuroimage 2005, 26(1), 810, 2005. C. G. Hanson, L. G. Hanson, A multi-frequency amplitude modulator for encoding electrical signals in MR images, Proc. of the ISMRM 14th Annual Meeting, 2388, 2006. L. G. Hanson, A. Skimminge, C. G. Hanson, Strategies for avoiding image artefacts when scanner is used for recording of non-MR signals, Proc. of the ISMRM 14th Annual Meeting, 2389, 2006. L. G. Hanson, A. Skimminge,C. G. Hanson, Encoding of EEG in MR images, Proc. of the ISMRM 15th Annual Meeting, 1958, 2007. L. G. Hanson, A. Skimminge,C. G. Hanson, Minimalist EEG-recording for improving fMRI. Proc. of the ISMRM 16th Annual Meeting, 2427, 2008.

L. G. Hanson, C. Dali, J. Fogh, Multi-slice spectroscopic imaging of late infantile metachromatic leukodystrophy, Proc. of the ISMRM 16th Annual Meeting, 2066, 2008. L. G. Hanson, H. Lund, I. K. Mikkelsen, Estimation of perfusion and other vascular parameters from rst part of bolus passage. Proc. of the ISMRM 17th Annual Meeting, 1470, 2009. C. Dali, L. G. Hanson, J. Fogh, A. M. Lund, Multi-slice proton MRSI and clinical outcome in children with late infantile Metachromatic Leukodystrophy (MLD). Proc. of the ISMRM 17th Annual Meeting, 1170, 2009. X. Wu, L. G. Hanson, M. Blinkenberg, A. Skimminge, P. S. Srensen, O. B. Paulson and H. K. Mathiesen. Cortical N-acetyl aspartate predicts long-term clinical disability in multiple sclerosis a longitudinal MR spectroscopic imaging study. Proc. of the ISMRM 18th Annual Meeting, 4330, 2010.