Table of Contents

VOL. 181
NO. 9 November 1, 2008 Pages In This Issue Letters to the Editor

5813 5813

Comment on Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections

Jiezhong Chen

Response to Comment on Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections
David K. Meyerholz, Michelle Edsen-Moore, Jodi McGill, Ruth A. Coleman, Robert T. Cook, and Kevin L. Legge

Pillars of Immunology

The Bubble Boy Paradox: An Answer That Led to a Question

Leslie J. Berg

Pillars Article: Interleukin-2 Receptor Chain Mutation Results in X-Linked Severe Combined Immunodeficiency in Humans. 1993. Cell 73: 147157.
Masayuki Noguchi, Huafang Yi, Howard M. Rosenblatt, Alexandra H.Filipovich, Stephen Adelstein, William S. Modi, O. Wesley McBride, and Warren J. Leonard

Brief Reviews

5829 Macrophages as APC and the Dendritic Cell Myth

David A. Hume

Cutting Edge
5837 Cutting Edge: Local Recall Responses by Memory T Cells Newly Recruited to Peripheral Nonlymphoid Tissues
Linda M. Wakim, Thomas Gebhardt, William R. Heath, and Francis R. Carbone
Cutting Edge: IFN- Enables APC to Promote Memory Th17 and Abate Th1 Cell Development
Ilona Kryczek, Shuang Wei, Wenrong Gong, Xiaogong Shu, Wojciech Szeliga, Linhua Vatan, Lieping Chen, Guobin Wang, and Weiping Zou
On the cover: Expansion of MAdCAM-1 marginal reticular cell (MRC) layer at the outermost region immediately underneath the subcapsular sinus of postnatally growing mesenteric lymph node (MLN). Immunofluorescent staining of MAdCAM-1 (orange) and laminin (green) in day 6 mouse MLN. MAdCAM-1 is also highly expressed by blood vessels (inner ring-like structures). Katakai, T., H. Suto, M. Sugai, H. Gonda, A. Togawa, S. Suematsu, Y. Ebisuno, K. Katagiri, T. Kinashi, and A. Shimizu. 2008. Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. J. Immunol. 181: 6189 6200. The Journal of Immunology (ISSN 0022-1767) is published twice each month by The American Association of Immunologists, Inc., 9650 Rockville Pike, Bethesda, MD 20814-3994, Phone: 301-634-7197, Fax: 301-634-7829. Subscription term: New subscriptions and renewals begin January 1 and expire one year later (see http://www.jimmunol.org/subscriptions for prices and details). A special rate is available to members of The American Association of Immunologists, Inc. (see http://www.aai.org/ membership). The American Association of Immunologists, Inc., is not responsible for undeliverable issues. Replacement issues can be obtained, if available, at the regular price of single issues (see http://www.jimmunol.org/pdf/single_issue_purchase.pdf). Reprints of individual articles are available only from authors. Periodicals postage paid at Bethesda, MD 20814-3994, and at additional mailing offices. Country of origin U.S.A. Printed on acid-free recyclable paper. Postmaster: Send address changes 60 days in advance to The Journal of Immunology, Subscription Department, 9650 Rockville Pike, Bethesda, MD 20814-3994. Copyright 2008 by The American Association of Immunologists, Inc.
Cellular Immunology and Immune Regulation
5847 Jakmip1 Is Expressed upon T Cell Differentiation and Has an Inhibitory Function in Cytotoxic T Lymphocytes
Valentina Libri, Dorte Schulte, Amber van Stijn, Josiane Ragimbeau, Lars Rogge, and Sandra Pellegrini
NF-B Modulates Sensitivity to Apoptosis, Proinflammatory and Migratory Potential in Short- versus Long-Term Cultured Human Lymphocytes
Marina Ferrarini, Fanny Delfanti, Monica Gianolini, Chiara Rizzi, Massimo Alfano, Adriano Lazzarin, and Priscilla Biswas
A Complex Interplay among Virus, Dendritic Cells, T Cells, and Cytokines in Dengue Virus Infections
Wanwisa Dejnirattisai, Thaneeya Duangchinda, Chen-Lung Steve Lin, Sirijitt Vasanawathana, Meleri Jones, Michael Jacobs, Prida Malasit, Xiao-ning Xu, Gavin Screaton, and Juthathip Mongkolsapaya
Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-
Melissa B. Uccellini, Liliana Busconi, Nathaniel M. Green, Patricia Busto, Sean R. Christensen, Mark J. Shlomchik, Ann Marshak-Rothstein, and Gregory A. Viglianti
E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors
Qi Yang, Lela Kardava, Anthony St. Leger, Kathleen Martincic, Barbara Varnum-Finney, Irwin D. Bernstein, Christine Milcarek, and Lisa Borghesi
Pathogenic Effector T Cell Enrichment Overcomes Regulatory T Cell Control and Generates Autoimmune Gastritis
Joao P. Monteiro, Julia Farache, Ana Carolina Mercadante, Julio A. Mignaco, Martin Bonamino, and Adriana Bonomo
A Quantitative Trait Locus on Chromosome 4 Affects Cycling of Hematopoietic Stem and Progenitor Cells through Regulation of TGF-2 Responsiveness

Serine Avagyan, Ludmila Glouchkova, Juhyun Choi, and Hans-Willem Snoeck
Fas Expression on Antigen-Specific T Cells Has Costimulatory, Helper, and Down-Regulatory Functions In Vivo for Cytotoxic T Cell Responses but Not for T Cell-Dependent B Cell Responses
Irina Puliaeva, Roman Puliaev, Andrei Shustov, Mark Haas, and Charles S. Via

5948 5956

SIT and TRIM Determine T Cell Fate in the Thymus
Uwe Koelsch, Burkhart Schraven, and Luca Simeoni
Identification of CD25 T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers
Kensuke Shibata, Hisakata Yamada, Risa Nakamura, Xun Sun, Momoe Itsumi, and Yasunobu Yoshikai
IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage
Gretta L. Stritesky, Norman Yeh, and Mark H. Kaplan
Experimental Extracorporeal Photopheresis Inhibits the Sensitization and Effector Phases of Contact Hypersensitivity via Two Mechanisms: Generation of IL-10 and Induction of Regulatory T Cells
Akira Maeda, Agatha Schwarz, Ann Bullinger, Akimichi Morita, David Peritt, and Thomas Schwarz
Rho-ROCK-Dependent Ezrin-Radixin-Moesin Phosphorylation Regulates Fas-Mediated Apoptosis in Jurkat Cells
Marylise Hebert, Sophie Potin, Michael Sebbagh, Jacques Bertoglio, Jacqueline Breard, and Jocelyne Hamelin

5974 5981

Heterospecific CD4 Help to Rescue CD8 T Cell Killers
Marie-Ghislaine de Goer de Herve, Anne Cariou, Federico Simonetta, and Yassine Taoufik
An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor
Maho Suzukawa, Motoyasu Iikura, Rikiya Koketsu, Hiroyuki Nagase, Chise Tamura, Akiko Komiya, Susumu Nakae, Kouji Matsushima, Ken Ohta, Kazuhiko Yamamoto, and Masao Yamaguchi
OX40 Costimulatory Signals Potentiate the Memory Commitment of Effector CD8 T Cells
Seyed Fazlollah Mousavi, Pejman Soroosh, Takeshi Takahashi, Yasunobu Yoshikai, Hao Shen, Leo Lefrancois, Jannie Borst, Kazuo Sugamura, and Naoto Ishii

6002 6010

TCR Complex-Activated CD8 Adhesion Function by Human T Cells
Jay C. Varghese and Kevin P. Kane
Estimation of the Size of the Alloreactive NK Cell Repertoire: Studies in Individuals Homozygous for the Group A KIR Haplotype
Cyril Fauriat, Sandra Andersson, Andreas T. Bjorklund, Mattias Carlsten, Marie Schaffer, Niklas K. Bjorkstrom, Bettina C. Baumann, Jakob Michaelsson, Hans-Gustaf Ljunggren, and Karl-Johan Malmberg
Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity
Wanhong Ding, Lori L. Stohl, John A. Wagner, and Richard D. Granstein
Intraclonal Competition Inhibits the Formation of High-Affinity Antibody-Secreting Cells
Thuc-vy L. Le, Tea Hyun Kim, and David D. Chaplin
Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4CD25LAP Regulatory T Cell and Is Associated with Down-Regulation of IL-17CD4ICOSCXCR5 Follicular Helper T Cells

Henry Yim Wu, Francisco J. Quintana, and Howard L. Weiner
IL-24 Induces Apoptosis of Chronic Lymphocytic Leukemia B Cells Engaged into the Cell Cycle through Dephosphorylation of STAT3 and Stabilization of p53 Expression
Alexander Sainz-Perez, Helene Gary-Gouy, Francoise Gaudin, Ghyath Maarof, Anne Marfaing-Koka, Thierry de Revel, ` and Ali Dalloul
Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis
Takafumi Yokota, Kenji Oritani, Karla P. Garrett, Taku Kouro, Makoto Nishida, Isao Takahashi, Michiko Ichii, Yusuke Satoh, Paul W. Kincade, and Yuzuru Kanakura
Anterior Pituitary Progenitor Cells Express Costimulatory Molecule 4Ig-B7-H3
Yasuhiro Nagai, Hisashi Aso, Hideki Ogasawara, Sachi Tanaka, Yoshikazu Taketa, Kouichi Watanabe, Shyuichi Ohwada, Michael T. Rose, Haruki Kitazawa, and Takahiro Yamaguchi
Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase during Thymocyte Development
Rustom Falahati and David Leitenberg
Central Tolerance Regulates B Cells Reactive with Goodpasture Antigen 3(IV)NC1 Collagen
Ying Zhang, Susan C. Su, Douglas B. Hecox, Graham F. Brady, Katherine M. Mackin, Amy G. Clark, and Mary H. Foster
An Epithelial Progenitor Pool Regulates Thymus Growth
William E. Jenkinson, Andrea Bacon, Andrea J. White, Graham Anderson, and Eric J. Jenkinson
Expression of CD86 on Human Islet Endothelial Cells Facilitates T Cell Adhesion and Migration
Biliana Lozanoska-Ochser, Nigel J. Klein, Guo C. Huang, Raymond A. Alvarez, and Mark Peakman
IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma
Chuanwang Song, Liqiong Luo, Zhang Lei, Bo Li, Zhihui Liang, Guanghui Liu, Dong Li, Guimei Zhang, Bo Huang, and Zuo-Hua Feng
Selective Expression Rather than Specific Function of Txk and Itk Regulate Th1 and Th2 Responses
Nisebita Sahu, Ana M. Venegas, Dragana Jankovic, Wayne Mitzner, Julio Gomez-Rodriguez, Jennifer L. Cannons, Connie Sommers, Paul Love, Alan Sher, Pamela L. Schwartzberg, and Avery August

Critical Role of TLR9 in Acute Graft-versus-Host Disease
Claudia Calcaterra, Lucia Sfondrini, Anna Rossini, Michele Sommariva, Cristiano Rumio, Sylvie Menard, and Andrea Balsari

6140 6148

Unique Receptor Repertoire in Mouse Uterine NK cells
Hakim Yadi, Shannon Burke, Zofia Madeja, Myriam Hemberger, Ashley Moffett, and Francesco Colucci
Immunosurveillance of Lung Melanoma Metastasis in EBI-3-Deficient Mice Mediated by CD8 T Cells
Kerstin A. Sauer, Joachim H. Maxeiner, Roman Karwot, Petra Scholtes, Hans A. Lehr, Mark Birkenbach, Richard S. Blumberg, and Susetta Finotto
Cross-Linking of B7-H1 on EBV-Transformed B Cells Induces Apoptosis through Reactive Oxygen Species Production, JNK Signaling Activation, and fasL Expression
Yeong Seok Kim, Ga Bin Park, Hyun-Kyung Lee, Hyunkeun Song, In-Hak Choi, Wang Jae Lee, and Dae Young Hur
Human NK Cells Kill Resting but Not Activated Microglia via NKG2D- and NKp46-Mediated Recognition
Anna Lunemann, Jan D. Lunemann, Susanne Roberts, Brady Messmer, Rosa Barreira da Silva, Cedric S. Raine, and Christian Munz
CX3CR1c-kit Bone Marrow Cells Give Rise to CD103 and CD103 Dendritic Cells with Distinct Functional Properties
Maria-Luisa del Rio, Jose-Ignacio Rodriguez-Barbosa, Jasmin Bolter, Matthias Ballmaier, Oliver Dittrich-Breiholz, Michael Kracht, Steffen Jung, and Reinhold Forster
Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs
Tomoya Katakai, Hidenori Suto, Manabu Sugai, Hiroyuki Gonda, Atsushi Togawa, Sachiko Suematsu, Yukihiko Ebisuno, Koko Katagiri, Tatsuo Kinashi, and Akira Shimizu
Mycobacterium bovis Bacille Calmette-Guerin Infection in the CNS Suppresses Experimental Autoimmune Encephalomyelitis and Th17 Responses in an IFN--Independent Manner
JangEun Lee, Emily K. Reinke, Alla L. Zozulya, Matyas Sandor, and Zsuzsanna Fabry
Molecular and Structural Immunology
6213 Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates

Sonia Schoonbroodt, Mieke Steukers, Malini Viswanathan, Nicolas Frans, Marie Timmermans, Anita Wehnert, Minh Nguyen, Robert Charles Ladner, and Rene M. Hoet

6222 6230

Transcription Factor Gfi1 Restricts B Cell-Mediated Autoimmunity
Chozhavendan Rathinam, Hans Lassmann, Michael Mengel, and Christoph Klein
Automated Identification of Complementarity Determining Regions (CDRs) Reveals Peculiar Characteristics of CDRs and B Cell Epitopes
Yanay Ofran, Avner Schlessinger, and Burkhard Rost
n-3 Polyunsaturated Fatty Acids Suppress the Localization and Activation of Signaling Proteins at the Immunological Synapse in Murine CD4 T Cells by Affecting Lipid Raft Formation
Wooki Kim, Yang-Yi Fan, Rola Barhoumi, Roger Smith, David N. McMurray, and Robert S. Chapkin
Loss of Protein Kinase C, Bcl10, or Malt1 Selectively Impairs Proliferation and NF-B Activation in the CD4 T Cell Subset
Lara M. Kingeter and Brian C. Schaefer
Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation
Lindsay L. Jones, Leremy A. Colf, Jennifer D. Stone, K. Christopher Garcia, and David M. Kranz

6265 6275

Ikaros Regulates Notch Target Gene Expression in Developing Thymocytes
Sheila Chari and Susan Winandy
Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing Regulates Quality of Processed Peptides Presented by MHC Class I Molecules
Takayuki Kanaseki and Nilabh Shastri

Immunogenetics

6283 Impact of Protective IL-2 Allelic Variants on CD4Foxp3 Regulatory T Cell Function In Situ and Resistance to Autoimmune Diabetes in NOD Mice
Evridiki Sgouroudis, Alexandre Albanese, and Ciriaco A. Piccirillo
Polymorphic Sites Away from the Bw4 Epitope That Affect Interaction of Bw4 HLA-B with KIR3DL1
Bharati Sanjanwala, Monia Draghi, Paul J. Norman, Lisbeth A. Guethlein, and Peter Parham
Complete Characterization of Killer Ig-Like Receptor (KIR) Haplotypes in Mauritian Cynomolgus Macaques: Novel Insights into Nonhuman Primate KIR Gene Content and Organization
Benjamin N. Bimber, Anna J. Moreland, Roger W. Wiseman, Austin L. Hughes, and David H. OConnor

Host Defense

6309 An Indispensable Role for the Chemokine Receptor CCR10 in IgA Antibody-Secreting Cell Accumulation
Olivier Morteau, Craig Gerard, Bao Lu, Sorina Ghiran, Miriam Rits, Yuko Fujiwara, Yuetching Law, Kathryn Distelhorst, Elizabeth M. Nielsen, Erica D. Hill, Raymond Kwan, Nicole H. Lazarus, Eugene C. Butcher, and Eric Wilson
A Novel Role of CD30L/CD30 Signaling by T-T Cell Interaction in Th1 Response against Mycobacterial Infection
Ce Tang, Hisakata Yamada, Kensuke Shibata, Hiromi Muta, Worawidh Wajjwalku, Eckhard R. Podack, and Yasunobu Yoshikai
Immune Evasion of Enterococcus faecalis by an Extracellular Gelatinase That Cleaves C3 and iC3b
Shin Yong Park, Yong Pyo Shin, Chong Han Kim, Ho Jin Park, Yeon Sun Seong, Byung Sam Kim, Sook Jae Seo, and In Hee Lee
Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoV
Fumihiko Yasui, Chieko Kai, Masahiro Kitabatake, Shingo Inoue, Misako Yoneda, Shoji Yokochi, Ryoichi Kase, Satoshi Sekiguchi, Kouichi Morita, Tsunekazu Hishima, Hidenori Suzuki, Katsuo Karamatsu, Yasuhiro Yasutomi, Hisatoshi Shida, Minoru Kidokoro, Kyosuke Mizuno, Kouji Matsushima, and Michinori Kohara
Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes
Markus Skold and Samuel M. Behar
Design, Expression, and Processing of Epitomized Hepatitis C Virus-Encoded CTL Epitopes
Daniel Yerly, David Heckerman, Todd Allen, Todd J. Suscovich, Nebojsa Jojic, Carl Kadie, Werner J. Pichler, Andreas Cerny, and Christian Brander
Long-Term Immunity against Actual Poxviral HLA Ligands as Identified by Differential Stable Isotope Labeling
Verena S. Meyer, Wolfgang Kastenmuller, Georg Gasteiger, Mirita Franz-Wachtel, Tobias Lamkemeyer, Hans-Georg Rammensee, Stefan Stevanovic, Dagmar Sigurdardottir, and Ingo Drexler
CCL3-CCR5 Axis Regulates Intratumoral Accumulation of Leukocytes and Fibroblasts and Promotes Angiogenesis in Murine Lung Metastasis Process

Yu Wu, Ying-Yi Li, Kouji Matsushima, Tomohisa Baba, and Naofumi Mukaida
Ly49h-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex
Nassima Fodil-Cornu, Seung-Hwan Lee, Simon Belanger, Andrew P. Makrigiannis, Christine A. Biron, R. Mark Buller, and Silvia M. Vidal
Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells
Tzong-Shi Lu, Hava Karsenty Avraham, Seyha Seng, Souvenir D. Tachado, Henry Koziel, Alexandros Makriyannis, and Shalom Avraham
Prolonged Microglial Cell Activation and Lymphocyte Infiltration following Experimental Herpes Encephalitis
Cristina P. Marques, Maxim C.-J. Cheeran, Joseph M. Palmquist, Shuxian Hu, Stina L. Urban, and James R. Lokensgard
Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF-B Activation via the DNA-Dependent Activator of IFN Regulatory Factors
William J. Kaiser, Jason W. Upton, and Edward S. Mocarski
Hepatitis C Virus Immune Escape via Exploitation of a Hole in the T Cell Repertoire
Matthias Wolfl, Alleluiah Rutebemberwa, Timothy Mosbruger, Qing Mao, Hong-mei Li, Dale Netski, Stuart C. Ray, Drew Pardoll, John Sidney, Alessandro Sette, Todd Allen, Thomas Kuntzen, Daniel G. Kavanagh, Jurgen Kuball, Philip D. Greenberg, and Andrea L. Cox
MyD88 Signaling Is Not Essential for Induction of Antigen-Specific B Cell Responses but Is Indispensable for Protection against Streptococcus pneumoniae Infection following Oral Vaccination with Attenuated Salmonella Expressing PspA Antigen
Sung-Moo Park, Hyun-Jeong Ko, Doo-Hee Shim, Jin-Young Yang, Yong-Ho Park, Roy Curtiss III, and Mi-Na Kweon

6456 6467

Expansion of Foxp3 Regulatory T Cells in Mice Infected with the Filarial Parasite Brugia malayi
Henry J. McSorley, Yvonne M. Harcus, Janice Murray, Matthew D. Taylor, and Rick M. Maizels
The Level of Hepatitis B Virus Replication Is Not Affected by Protein ISG15 Modification but Is Reduced by Inhibition of UBP43 (USP18) Expression
Jung-Hwan Kim, Jiann-Kae Luo, and Dong-Er Zhang

Inflammation

6473 Functional Dichotomy of Dendritic Cells following Interaction with Leishmania braziliensis: Infected Cells Produce High Levels of TNF-, whereas Bystander Dendritic Cells Are Activated to Promote T Cell Responses

Lucas P. Carvalho, Edward J. Pearce, and Phillip Scott

6503 6514

Signaling through MyD88 Regulates Leukocyte Recruitment after Brain Injury
Alicia A. Babcock, Henrik Toft-Hansen, and Trevor Owens
Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes
Hajo Haase, Julia L. Ober-Blobaum, Gabriela Engelhardt, Silke Hebel, Antje Heit, Holger Heine, and Lothar Rink
IL-4-Induced Selective Clearance of Oligomeric -Amyloid Peptideby Rat Primary Type 2 Microglia
Eisuke Shimizu, Kohichi Kawahara, Makoto Kajizono, Makoto Sawada, and Hitoshi Nakayama
12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo
Vincent Dioszeghy, Marcela Rosas, Benjamin H. Maskrey, Chantal Colmont, Nicholas Topley, Pavlos Chaitidis, Hartmut Kuhn, Simon A. Jones, Philip R. Taylor, and Valerie B. ODonnell
Human Plasmacytoid Dendritic Cells Interact with gp96 via CD91 and Regulate Inflammatory Responses
AnnaMaria De Filippo, Robert J. Binder, Chiara Camisaschi, Valeria Beretta, Flavio Arienti, Antonello Villa, Pamela Della Mina, Giorgio Parmiani, Licia Rivoltini, and Chiara Castelli
Differential Regulation of Chemokines by IL-17 in Colonic Epithelial Cells
Jimmy W. Lee, Ping Wang, Michael G. Kattah, Sawsan Youssef, Lawrence Steinman, Kathryn DeFea, and Daniel S. Straus
CCR5 Deficiency Aggravates Crescentic Glomerulonephritis in Mice
Jan-Eric Turner, Hans-Joachim Paust, Oliver M. Steinmetz, Anett Peters, Catherine Meyer-Schwesinger, Felix Heymann, Udo Helmchen, Susanne Fehr, Richard Horuk, Ulrich Wenzel, Christian Kurts, Hans-Willi Mittrucker, Rolf A. K. Stahl, and Ulf Panzer
Reversal of Thymic Stromal Lymphopoietin-Induced Airway Inflammation through Inhibition of Th2 Responses
Baohua Zhou, Mark B. Headley, Theingi Aye, Joel Tocker, Michael R. Comeau, and Steven F. Ziegler
Activation of an Immunoregulatory and Antiviral Gene Expression Program in Poly(I:C)-Transfected Human Neutrophils
Nicola Tamassia, Vincent Le Moigne, Marzia Rossato, Marta Donini, Stephen McCartney, Federica Calzetti, Marco Colonna, Flavia Bazzoni, and Marco A. Cassatella
Analysis of CD97 Expression and Manipulation: Antibody Treatment but Not Gene Targeting Curtails Granulocyte Migration
Henrike Veninga, Susann Becker, Robert M. Hoek, Manja Wobus, Elke Wandel, Jos van der Kaa, Martin van der Valk, Alex F. de Vos, Hannelore Haase, Bronwyn Owens, Tom van der Poll, Rene A. W. van Lier, J. Sjef Verbeek, Gabriela Aust, and Jorg Hamann
Up-Regulation of Vascular Endothelial Growth Factor-D Expression in Clear Cell Renal Cell Carcinoma by CD74: A Critical Role in Cancer Cell Tumorigenesis
Yu-Huei Liu, Chang-Yueh Lin, Wei-Chou Lin, Sai-Wen Tang, Ming-Kuen Lai, and Jung-Yaw Lin

Clinical Immunology

6595 Carcinoembryonic Antigen-Specific but Not Antiviral CD4 T Cell Immunity Is Impaired in Pancreatic Carcinoma Patients
Elena Tassi, Francesca Gavazzi, Luca Albarello, Vladimir Senyukov, Renato Longhi, Paolo Dellabona, Claudio Doglioni, Marco Braga, Valerio Di Carlo, and Maria Pia Protti
Immunodominant Epitopes in Herpes Simplex Virus Type 2 Glycoprotein D Are Recognized by CD4 Lymphocytes from Both HSV-1 and HSV-2 Seropositive Subjects
Min Kim, Janette Taylor, John Sidney, Zorka Mikloska, Neil Bodsworth, Katerina Lagios, Heather Dunckley, Karen Byth-Wilson, Martine Denis, Robert Finlayson, Rajiv Khanna, Alessandro Sette, and Anthony L. Cunningham
Strategic Nonmyeloablative Conditioning: CD154:CD40 Costimulatory Blockade at Primary Bone Marrow Transplantation Promotes Engraftment for Secondary Bone Marrow Transplantation after Engraftment Failure
Hong Xu, Yiming Huang, Paula M. Chilton, Lala-Rukh Hussain, Michael K. Tanner, Jun Yan, and Suzanne T. Ildstad
Characterization of the Antibody Response against NeuGcGM3 Ganglioside Elicited in Non-Small Cell Lung Cancer Patients Immunized with an Anti-Idiotype Antibody
Ana Mara Hernandez, Darien Toledo, Darel Martnez, Tania Grinan, Victor Brito, Amparo Macas, Sailyn Alfonso, Teresa Rondon, Eduardo Suarez, Ana Mara Vazquez, and Rolando Perez
Activation of Antigen-Specific Cytotoxic T Lymphocytes by 2-Microglobulin or TAP1 Gene Disruption and the Introduction of Recipient-Matched MHC Class I Gene in Allogeneic Embryonic Stem Cell-Derived Dendritic Cells
Yusuke Matsunaga, Daiki Fukuma, Shinya Hirata, Satoshi Fukushima, Miwa Haruta, Tokunori Ikeda, Izumi Negishi, Yasuharu Nishimura, and Satoru Senju
Immunization with a Mimotope of GD2 Ganglioside Induces CD8 T Cells That Recognize Cell Adhesion Molecules on Tumor Cells
Andrzej Wierzbicki, Margaret Gil, Michael Ciesielski, Robert A. Fenstermaker, Yutaro Kaneko, Hanna Rokita, Joseph T. Lau, and Danuta Kozbor
Bone Marrow-Derived IFN-Producing Killer Dendritic Cells Account for the Tumoricidal Activity of Unpulsed Dendritic Cells

Nourredine Himoudi, Stephen Nabarro, Jo Buddle, Ayad Eddaoudi, Adrian J. Thrasher, and John Anderson
Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions
Lucie Baudino, Yasuro Shinohara, Falk Nimmerjahn, Jun-Ichi Furukawa, Munehiro Nakata, Eduardo Martnez-Soria, Franz Petry, Jeffery V. Ravetch, Shin-Ichiro Nishimura, and Shozo Izui
LETTERS OF RETRACTION Retraction: Dual Effect of AMD3100, a CXCR4 Antagonist, on Bleomycin-Indiced Lung Inflammation
Masaki Watanabe, Yuko Shirahama, Hideo Mitsuyama, Ken-ichi Oonakahara, Satoshi Noma, Ikkou Higashimoto, Mitsuhiro Osame, and Kimiyoshi Arimura
Retraction: Suppression of Discoidin Domain Receptor 1 by RNA Interference Attenuates Lung Inflammation
Masaki Watanabe, Yuko Shirahama, Ryuki Hirano, Hideo Mitsuyama, Ikkou Higashimoto, Mitsuhiro Osame, and Kimiyoshi Arimura
Retraction: Activation of Discoidin Domain Receptor 1 on CD14-Positive Bronchoalveolar Lavage Fluid Cells Induces Chemokine Production in Idiopathic Fibrosis
Masaki Watanabe, Yuko Shirahama, Ken-ichi Oonakahara, Ikkou Higashimoto, Mitsuhiro Osame, and Kimiyoshi Arimura

AUTHOR INDEX